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Treatment of Drug-Induced Erythema Multiforme: Case Report

Journal of Oral Medicine and Pain 2019³â 44±Ç 4È£ p.183 ~ 188
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ÀÌÇØ¿Á ( Lee Hae-Ohk ) - Pusan National University School of Dentistry Department of Oral Medicine
ÁÖÇý¹Î ( Ju Hye-Min ) - Pusan National University School of Dentistry Department of Oral Medicine
ÀÌÁö¿¬ ( Lee Ji-Yeon ) - Pusan National University School of Dentistry Department of Oral Medicine
ÀüÇý¹Ì ( Jeon Hye-Mi ) - Pusan National University Hospital Dental Clinic Center
±è°æÈñ ( Kim Kyung-Hee ) - Inje University Busan Paik Hospital Department of Oral Medicine
¿Á¼ö¹Î ( Ok Soo-Min ) - Pusan National University School of Dentistry Department of Oral Medicine
¾È¿ë¿ì ( Ahn Yong-Woo ) - Pusan National University School of Dentistry Department of Oral Medicine
Á¤¼ºÈñ ( Jeong Sung-Hee ) - Pusan National University School of Dentistry Department of Oral Medicine

Abstract


Erythema multiforme (EM) is an inflammatory immune-mediated mucosal disease. EM is classified as EM minor or EM major, depending on the severity of symptoms. Most patients with minor or major forms of EM have oral lesions. EM can occur as a result of adverse drug reactions but this is difficult to establish. Several indicators have been developed that can be used as a criterion of evaluation to ensure objectivity in identifying the causality of adverse drug reactions. The Naranjo algorithm was used in the evaluation to ensure objectivity in identifying the causality of adverse drug reactions. There were two cases of patients suspected of having EM induced by drugs. They were both assessed using the Naranjo algorithm to confirm the causality of the disease.

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Drug-related side effects and adverse reactions; Erythema multiforme; Rheumatoid arthritis

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